This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by He, X.-w. Articles by Cheng, T. O. Search for Related Content PubMed PubMed Citation Articles by He, X.-w. Articles by Cheng, T. O. Social Bookmarking                         What's this?

Subacute Cor Pulmonale Due to Tumor Embolization to the Lungs

General Hospital of Shenyang Command People's Liberation Army, Shenyang, China, The George Washington University School of Medicine and Health Sciences, Washington, D.C.

Yi-hai Tang, M.D.

General Hospital of Shenyang Command People's Liberation Army, Shenyang, China, The George Washington University School of Medicine and Health Sciences, Washington, D.C.

Zhong-qiang Luo, M.D.

General Hospital of Shenyang Command People's Liberation Army, Shenyang, China, The George Washington University School of Medicine and Health Sciences, Washington, D.C.

Lian-di Gong, M.D.

General Hospital of Shenyang Command People's Liberation Army, Shenyang, China, The George Washington University School of Medicine and Health Sciences, Washington, D.C.

Tsung O. Cheng, M.D., F.A.C.A., F.I.C.A.

General Hospital of Shenyang Command People's Liberation Army, Shenyang, China, The George Washington University School of Medicine and Health Sciences, Washington, D.C.

Six patients with subacute cor pulmonale due to tumor embolization to the lungs were reported from China. Five of the 6 patients suffered from progressive unrelenting dyspnea; 4 had completely normal cardiopulmonary findings on physical examination. Four of the 5 patients who had chest roentgenograms showed diffuse bilateral mottling of the lungs with no evidence of cardiomegaly. At autopsy right ventricular hypertrophy was present in all. The pathologic findings in the lungs consisted of multiple microscopic tumor emboli distributed diffusely in the pulmonary arterioles and/or perivascular lymphatics; the lumen of these vessels was obliterated with or without hyperplastic endarteritis. Although the outcome of this not uncommon clinicopathologic entity is generally fatal, early diagnosis followed by prompt effective therapy for the underlying primary neoplasm has been reported to prolong survival.

Angiology, Vol. 40, No. 1, 11-17 (1989)
DOI: 10.1177/000331978904000103


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?