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Hemorheologic Factors in the Postacute Phase of Ischemic Stroke

2nd Department of Internal Medicine, Gerontologic and Geriatric Chair, Faculty of Medicine, University of Perugia, Perugia, Italy

Michele Mercuri

2nd Department of Internal Medicine, Gerontologic and Geriatric Chair, Faculty of Medicine, University of Perugia, Perugia, Italy

Lucilla Parnetti

2nd Department of Internal Medicine, Gerontologic and Geriatric Chair, Faculty of Medicine, University of Perugia, Perugia, Italy

Graziana Lupattelli

2nd Department of Internal Medicine, Gerontologic and Geriatric Chair, Faculty of Medicine, University of Perugia, Perugia, Italy

Umberto Senin

2nd Department of Internal Medicine, Gerontologic and Geriatric Chair, Faculty of Medicine, University of Perugia, Perugia, Italy

Clinical and hemorheologic data were recorded in a homogeneous group of 72 patients (age range sixty-one to seventy years), suffering from ischemic stroke with an onset of less than eight hours, confirmed clinically and by com puterized tomography. A quantitative neurologic analysis and the following he morheologic parameters were monitored for twenty weeks following the acute episode: fibrinogen, total proteins, albumin, hematocrit, leukocyte and platelet counts, whole blood filterability (WBF), red blood cell deformability (RBCD), and blood plasma, and serum viscosity. The results show a significant decrease in hematocrit values parallel to the clinical neurologic improvement and a sig nificant increase in RBCD in the patients with the better clinical recovery. These data confirm the role of hemorheologic parameters in the clinical follow-up of cerebrovascular disorders.

Angiology, Vol. 39, No. 5, 437-448 (1988)
DOI: 10.1177/000331978803900506


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