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Noninvasvie Testing of Cerebral Perfusion Reserve Prior to Coronary Artery Bypass Graft Surgery

William S. Middleton Memorial Veterans' Administration Hospital, Madison, Wisconsin, From the Department of Neurology, University of Wisconsin, Madison, Wisconsin

Hans L. Lagreze

From the Department of Neurology, University of Wisconsin, Madison, Wisconsin

Herbert A. Berkoff

From the Department of Surgery, University of Wisconsin, Madison, Wisconsin

William D. Thrnipseed

From the Department of Surgery, University of Wisconsin, Madison, Wisconsin

Joan M. Hanson

From the Department of Neurology, University of Wisconsin, Madison, Wisconsin

John J. Sunderland

From the Department of Radiology/Medical Physics, University of Wisconsin, Madison, Wisconsin

Robert J. Nickles

From the Department of Radiology/Medical Physics, University of Wisconsin, Madison, Wisconsin

Bruce R. Rowe

From the Department of Radiology/Medical Physics, University of Wisconsin, Madison, Wisconsin

Cerebral perfusion reserve testing using fluorine-18-fluoromethane and pos itron emission tomographic brain scanning to define cerebral blood flow abnor malities was performed in 5 patients being considered for combined coronary and carotid reconstructive surgery. Blood flow testing during normocapnia and following hypercapnia was utilized in these patients to determine the hemody namic significance of known extracranial carotid artery occlusive lesions. Re serve diminution in 2 of these patients prompted combined surgery, whereas normal reserve values in the other 3 prompted coronary surgery alone. Results obtained in this preliminary series show how preoperative noninvasive testing of cerebral perfusion reserve adds to the diagnostic evaluation of patients with widespread vascular disease.

Angiology, Vol. 39, No. 5, 421-428 (1988)
DOI: 10.1177/000331978803900504


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