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Prolonged Beneficial Effects of Dobutamine in Refractory Heart Failure—Case Histories

From the Department of Medicine (Cardiology), Veterans Administration Medical Center, Big Spring, Texas, Department of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas

Jack Margolis

Department of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas

Vijayalakshmi Puram

From the Department of Medicine (Cardiology), Veterans Administration Medical Center, Big Spring, Texas, Department of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas

Two patients with refractory congestive heart failure were treated with do butamine for forty-eight to seventy-two hours with close monitoring of weight and symptomatology. After two to four cycles of dobutamine treatment, 1 pa tient showed sustained hemodynamic benefit after six months, whereas the sec ond patient had partial improvement. At the end of a one-year follow-up, both had sustained improvement in effort tolerance, documented by a stress test. The quality of life has markedly improved, and they have not required further hos pital care.

Angiology, Vol. 38, No. 8, 631-634 (1987)
DOI: 10.1177/000331978703800810


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