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Holt-Oram Syndrome in a Puerto Rican Family —Case Reports

Department of Medicine, The George Washington University School of Medicine and Health Sciences, Washington, D.C.

The Holt-Oram syndrome is reported for the first time in a Puerto Rican family of one mother and two daughters. All had severe upper limb anomalies and secundum atrial septal defect. One daughter, the proband, had, in addition, a persistent left superior vena cava, a cardiac anomaly that has not been previ ously reported in association with the Holt-Oram syndrome.

Angiology, Vol. 38, No. 12, 896-902 (1987)
DOI: 10.1177/000331978703801205


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