This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Ohta, H. Articles by Hattori, N. Search for Related Content PubMed PubMed Citation Articles by Ohta, H. Articles by Hattori, N. Social Bookmarking                         What's this?

The Long Term Effects of Percutaneous Transluminal Angioplasty for Treating Patients with Renovascular Hypertension: Case Studies

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Toshikazu Takabatake

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Yoshiharu Yamamoto

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Yoh-ichi Ishida

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Hiromoto Hara

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Yasuyuki Ushiogi

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Saburo Nakamura

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Masahiko Kawabata

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Naoteru Hashimoto

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Tohru Sasaki

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Shigehiko Sato

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Yuh-ji Yamada

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Nobu Hattori

First Department of Internal Medicine, School of Medicine, Kanazawa University, Kanazawa, Japan

Percutaneous transluminal angioplasty was performed on 10 patients with unilateral renovascular hypertension (7 with atheromatous and 3 with fibro muscular stenoses) who were then followed for an average of 42 months (range, 24 to 67 months). Dilatation of the stenosis was initially successful in all patients except one who had severe atheromatous stenosis. Among patients with ather omatous disease, normotension was attained for 40, 25 and 24 months in 3 patients given no antihypertensive medication and for 67 and 55 months in 2 patients given only nicardipine. The remaining one patient had a recurrent stenosis 3 months after angioplasty. All patients with fibromuscular dysplasia have been normotensive without any hypotensive medication for more than 4 years. Plasma renin activity declined within one week after angioplasty and remained unchanged thereafter in all patients except the one case suffering from a recurrent stenosis. Renal blood flow and glomerular filtration rate re mained increased after angioplasty. These results suggest that hypertension can be controlled and renal dysfunction in patients with renal artery stenosis caused by atheroma or fibromuscular dysplasia improved for long periods by percuta neous transluminal angioplasty. The antihypertensive effect obtained by this procedure was more valuable for the patients with fibromuscular dysplasia than in those with atheromatous disease.

Angiology, Vol. 37, No. 7, 535-542 (1986)
DOI: 10.1177/000331978603700708


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?