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A Quantitative Test for Measuring Reactivity to Cold by the Digital Plethysmograph TechniqueApplication to 66 control subjects and 65 patients with Raynaud's phenomenon
Centre Hospital Regional De Nantes Hotel Dieu Place Alexis Ricordeau 44035 Nantes Cedex, France The authors have developed a vascular reactivity test to cold using the digital plethysmograph technique with a mercury strain gauge. Three types of arterial reactivity were determined: local reactivity after immersion of the hand in 11°C water, general reactivity after thorax ventilation, and cumulative reactivity as sociating both of these cooling modes. The method is based on measurement of the digital plethysmographic signal expressed as a ratio of a reference warm amplitude obtained after immersion of the hand in 45°C water for 3 min. The method was tested and perfected in 66 control subjects before being applied to 65 patients with Raynaud's disease. Significant differences were noted between these 2 groups, especially in cumulative reactivity (p < 10-9), which led to nu merical expression of results in 5 types of increasingly important reactivity. It would appear that the test has diagnostic and prognostic value in the explora tion of vascular acrosyndromes and their therapeutic follow-up.
Angiology, Vol. 37, No. 6,
433-439 (1986) |
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