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Development of Pulmonary Aneurysm in Primary Pulmonary Hypertension: A Case ReportFrom the Department of Cardiology, University Hospital Eppendorf, Hamburg, West Germany
From the Department of Nuclear Medicine, University Hospital Eppendorf, Hamburg, West Germany
From the Department of Nuclear Medicine, University Hospital Eppendorf, Hamburg, West Germany
From the Department of Cardiology, University Hospital Eppendorf, Hamburg, West Germany
From the Department of Cardiology, University Hospital Eppendorf, Hamburg, West Germany Selected cases of severe primary pulmonary arterial hypertension and asso ciated pulmonary vascular disease have been related to the oral ingestion of aminorex fumarate, an anorexigen obviously responsible for an epidemic of primary pulmonary hypertension in Western Europe between 1967 and 1970. This report describes a fifteen year follow-up of a female patient with aminorex fumarate related pulmonary hypertension and the uncommon finding of the formation of an excessive fusiform pulmonary trunk aneurysm in the late stage of the disease process. The progressive clinical course was followed by serial chest x-ray films and repeat right heart catheterization. The diagnosis of a main stem pulmonary artery aneurysm was noninvasively established by two-dimen sional echocardiography and confirmed by contrast-enhanced computed tomo graphy and radionuclide blood pool imaging. The patient is alive, thus no histologic correlate of this entity is available at present.
Angiology, Vol. 37, No. 4,
319-324 (1986) |
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