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Angiology
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Effect of Different Amounts of Blood Transfusion Given at Different Speeds on Left Ventricular Filling Pressure in Cases of Chronic Severe Anemia

Nitya Nand

Postgraduate Department of Medicine and Biochemistry, Medical College Hospital, Rohtak, India

M.S. Gupta

Postgraduate Department of Medicine and Biochemistry, Medical College Hospital, Rohtak, India

Manju Sharma

Postgraduate Department of Medicine and Biochemistry, Medical College Hospital, Rohtak, India

Pulmonary capillary 'wedge' pressure (PCWP) was measured before and after transfusion of 1 and 2 units of blood @ 5 and 10 ml/min. in 40 adult cases of chronic severe anemia (CSA). The cases were randomly divided into 4 sub groups of 10 cases each.

Following blood transfusion (BT), PCWP increased significantly in all the 4 subgroups (p < 0.001). The highest rise in PCWP was recorded when 2 units of blood were transfused at a rate of 10 ml/min, and the rise was minimum when 1 unit of blood was transfused @ 5 ml/min. Out of the two variables—speed and amount of BT—the amount was more important.

It is, therefore, concluded that administration of 2 units of blood in case of CSA at a rate of 5 or 10 ml/min is not desirable and that transfusion of 1 unit of blood @ 5 ml/min is quite safe.

Angiology, Vol. 37, No. 4, 281-284 (1986)
DOI: 10.1177/000331978603700403
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