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Future/Novel Uses of Beta Blockers in Clinical TherapeuticsUniversity of Dundee and the Tayside Health Board, Dundee, Scotland Beta-blocker usage in the United Kingdom centers around propranolol and oxprenolol as noncardioselective drugs, atenolol and metoprolol as cardioselec tive agents, and pindolol or oxprenolol when partial agonist activity is desired. Any meaningful comparison of a novel beta blocker against the established drugs must be a variable-dose trial, for the optimum dose of any beta blocker that can be tolerated varies widely. Effective beta blockade is considered to have been achieved when the standing heart rate has been lowered to about 55 beats- /minute.
Angiology, Vol. 37, No. 3,
218-220 (1986) |
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