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Angiology
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Hemostatic Balance Index in TIA Patients: Sex-Related Changes

Gualtiero Lippi

From the Department of Endocrinology, Medical Genetics and Clinical Chemistry, University of Florence, Florence, Italy

G. Arnetoli

From the Second Neurological Institute, University of Florence, Florence, Italy

R. Accardi

From the Second Neurological Institute, University of Florence, Florence, Italy

A. Doni

From the Department of Endocrinology, Medical Genetics and Clinical Chemistry, University of Florence, Florence, Italy

In order to evaluate the occurrence of hemostatic disorders, 37 patients with transient ischemic attacks (TIAs) and 50 control subjects were studied by means of the Hemostatic Balance Index (H.B.I.) derived from Raby's Thrombo dynamic Potential Index (T.P.I.) and Fearnley's Whole Blood Diluted Lysis Time (W.B.D.L.T.). Results showed a significant increase in T.P.I. and a ten dency to a decrease in fibrinolytic activity in the TIA group: H.B.I. was shown to be significantly increased, thus indicating a pro-thrombotic imbalance in these patients. The occurrence of similar changes in TIA females when com pared to male patients marks the importance of plasmatic factors in the mech anism of thrombotic disorders in females with cerebrovascular disease.

Angiology, Vol. 36, No. 7, 425-430 (1985)
DOI: 10.1177/000331978503600704
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