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Evaluation of Quinidine Short and Long-Acting in Control of Arrhythmias

Medical Service VA Medical Center, Long Beach, California, Department of Medicine, University of California, Irvine, California

Neil Pugash

Medical Service VA Medical Center, Long Beach, California, Department of Medicine, University of California, Irvine, California

Frank Toppo

Medical Service VA Medical Center, Long Beach, California, Department of Medicine, University of California, Irvine, California

Twenty-one patients with arrhythmias responsive to quinidine were studied both with regard to consistency of response as determined by repeat Holter Monitoring and in half of these patients a comparison of short and long-acting quinidine was made. Holter Monitoring demonstrated greater than 60% reduc tion of ectopic activity in all but one patient and reproducibility varied by less than 10% in nineteen of twenty-one patients. Nine of eleven patients showed the same response to long-acting quinidine as compared to short-acting. Eight of nine patients having significant numbers of ectopic pairs showed a significant reduction with quinidine therapy, both short-acting and long-acting.

Angiology, Vol. 35, No. 9, 581-590 (1984)
DOI: 10.1177/000331978403500907


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