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Clinical Significance of the Radioisotope Test Using I-131 Labelled Serum Albumin for Evaluating the Peripheral Circulation in the Foot During a Period of Reactive Hyperemia

Department of Physiology, University Center Limburg, Diepenbeek, Belgium, Department of Medicine, O.C.M.W. Hospital, Bree, Belgium

P. Steels

Department of Physiology, University Center Limburg, Diepenbeek, Belgium, Department of Medicine, O.C.M.W. Hospital, Bree, Belgium

The radioisotope test using I-131 labelled serum albumin, performed during a period of reactive hyperemia, provides quantitative data which express the rate at which radioactive blood flowing from the leg replaces the non radioactive blood present in the foot. It has been applied in normal subjects and in patients with arterial occlusions in the lower limbs. High washout rates, i.e. small M/2 index values, were found in the former, whereas low washout rates with higher M/2 indices were observed in the latter. Surprisingly, patients with a very low washout rate could be without subjective symptoms. The usefulness of the test in clinical practice is explained.

Angiology, Vol. 34, No. 2, 91-101 (1983)
DOI: 10.1177/000331978303400203


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