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Improved Exercise Myocardial Perfusion During Lidoflazine Therapy

Medical Service, Cardiovascular Section, Veterans Administration Medical Center, University of Texas Southwestern Medical School, Dallas, Texas

Kenneth A. Narahara

Harbor-UCLA Medical Center, Torrence, California

Janet Park

Medical Service, Cardiovascular Section, Veterans Administration Medical Center

Lidoflazine is a synthetic drug with calcium-channel blocking effects. In a study of 6 patients with severe classic angina pectoris, single-blind administra tion of lidoflazine was associated with improved myocardial perfusion during exercise as determined by thallium-201 stress scintigraphy. These studies demonstrate that lidoflazine therapy is associated with relief of angina, an increased physical work capacity, and improved regional myocardial perfusion during exercise.

Angiology, Vol. 34, No. 11, 705-710 (1983)
DOI: 10.1177/000331978303401103


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