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Nutritional & Pharmacologic Management of Hyperlipoproteinemia

118 Lankenau Medical Building City Line at Lancaster Pike Philadelphia, PA 19151

The results of the nutritional intervention on one of the twenty MRFIT centers is presented. The reduction in cholesterol was 5.78% after four years. Those results were compared with the changes found in serum cholesterol with a similar diet and the administration of either clofibrate or gemfibrozil. The reduction with clofibrate remained at 5%. However with gemfibrozil the reduction in cholesterol was 16%. The HDL level rose in half of these patients treated with either clofibrate or gemfibrozil. The results without concurrent dietary restriction usually show a greater reduction in VLDL and a greater rise in HDL than we found when nutritional and pharmacologic intervention were combined.

Angiology, Vol. 33, No. 9, 577-580 (1982)
DOI: 10.1177/000331978203300903


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