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All in the Family: Matrimonial Mitral Valve Clicks

Institute for Cardiovascular Diseases, Good Samaritan Hospital, Phoenix, Arizona

S. Ismail Bokhari

Institute for Cardiovascular Diseases, Good Samaritan Hospital, Phoenix, Arizona

Alberto Benchimol

Institute for Cardiovascular Diseases, Good Samaritan Hospital, Phoenix, Arizona

David Romney

Institute for Cardiovascular Diseases, Good Samaritan Hospital, Phoenix, Arizona

Mitral valve clicks with or without late systolic murmurs were detected in genetically unrelated marital partners of 5 families. The first family repre sented 2 successive nonconsanguineous marital unions with 3 generations of mitral valve clicks. The second family included 1 natural and 2 adopted children with clinical and echographic evidence of mitral valve prolapse. The third family was comprised of asymptomatic parents, both with nonejection clicks and mitral valve prolapse, whose daughter presented 3 years previously with syncope, palpitations, and combined mitral and tricuspid valve prolapse. The fourth family had 3 members with auscultatory and ultrasonic manifes tations of billowing mitral valve, whereas the fourth member had "silent mitral valve prolapse." The fifth family represented a mother with auscul tatory and echographic evidence of mitral valve prolapse; her 14-year-old daughter had both mitral and tricuspid valve prolapse, whereas the son had a bicuspid aortic valve. Both children were products of a prior marriage, and her husband has symptomatic mitral valve prolapse. We conclude that matrimonial mitral valve prolapse probably reflects the purported (6-10%) prevalence of this disorder in the general population. The consequences of such marital union on progeny is currently unclear and warrants future investigation.

Angiology, Vol. 32, No. 5, 355-360 (1981)
DOI: 10.1177/000331978103200509


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