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Angiology
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Effects of Buflomedil on Erythrocyte Deformability

J.A. Dormandy

St. James' Hospital and Department of Hemorrheology, St. George's Hospital Medical School, London, England

E. Ernst

St. James' Hospital and Department of Hemorrheology, St. George's Hospital Medical School, London, England

This brief communication outlines re cent experiments on the effects of buflo medil, a new vasoactive agent, on red cell deformability in patients with leg ischemia. In this randomized, double-blind cross-over study, 10 patients received 200 mg buflomedil and matching placebo intravenously. Red cell filterability in these patients was significantly improved after buflomedil administration versus baseline values with no significant change in filterability versus baseline after placebo administration.

Angiology, Vol. 32, No. 10, 714-716 (1981)
DOI: 10.1177/000331978103201008
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This article has been cited by other articles:


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 ANGIOLOGYHome page
E. Mannarino, L. Pasqualini, G. Maragoni, and U. Orlandi
Effect of Buflomedil Chlorhydrate on Local Oxygen Delivery in Peripheral Vascular Disease
Angiology, June 1, 1989; 40(6): 559 - 562.
[Abstract] [PDF]

Home page
 ANGIOLOGYHome page
S. Kobayashi, S. Yamaguchi, K. Okada, M. Kitani, K. Yamashita, K. Shimote, and T. Tsunematsu
Effect of Long-Term Administration of Buflomedil on Regional Cerebral Blood Flow in Chronic Cerebral Infarction
Angiology, January 1, 1988; 39(11): 934 - 941.
[Abstract] [PDF]


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