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Angiology
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Platelet Aggregation Measured by the Screen Filtration Pressure Method in Hypertensive Patients

A. Pagnan

Clinica Medica , Policlinico Universitario, via Giustiniani 2, 35100 Padova, Italy

A. Faggiotto

Clinica Medica , Policlinico Universitario, via Giustiniani 2, 35100 Padova, Italy

A. Visona

Clinica Medica , Policlinico Universitario, via Giustiniani 2, 35100 Padova, Italy

S. Davanzo

Clinica Medica , Policlinico Universitario, via Giustiniani 2, 35100 Padova, Italy

A.C. Pessina

Clinica Medica , Policlinico Universitario, via Giustiniani 2, 35100 Padova, Italy

C. Dal Palú

Clinica Medica , Policlinico Universitario, via Giustiniani 2, 35100 Padova, Italy

In this study platelet aggregation was measured by the screen filtration pressure method in 2 groups of hypertensives separated according to age. They were perfectly matched for levels of various "risk factors", with normotensive "controls".

No significant difference in platelet aggregate filtration pressure (PAFP) was found between hypertensives and normotensives. Contrary to normoten sive subjects, there was no significant increase in the PAFP values with age in the hypertensives. This might be due to the significantly higher blood urea values in the hypertensives as compared to the normotensives. An inverse relationship between blood urea concentration and PAFP values was in fact confirmed by in vivo and in vitro studies.

Angiology, Vol. 31, No. 11, 760-766 (1980)
DOI: 10.1177/000331978003101104
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