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Angiology
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Corticosteroids in Acute Myocardial Infarction

Charles A. Bush

From the Division of Cardiology, Wayne State and VA Medical Center, Allen Park, Michigan

William Renner

From the Division of Cardiology, Wayne State and VA Medical Center, Allen Park, Michigan

Harisios Boudoulas

From the Division of Cardiology, Wayne State and VA Medical Center, Allen Park, Michigan

Forty-two patients admitted to the Coronary Care Unit with a diagnosis of acute myocardial infarction were studied within 24 hours of the onset of symp toms. In addition to therapy determined by the attending physician, there was a double-blinded administration of either a placebo or methylprednisolone, 30 mg/kg intravenously every 6 hours for four doses. This drug had no beneficial effect on infarct size, dysrhythmias, complications, or left ventricular function 2 weeks after infarction.

Angiology, Vol. 31, No. 10, 710-714 (1980)
DOI: 10.1177/000331978003101007
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