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Effect of Potassium Infusion on the Human Conduction System

Department of Medicine The Methodist Hospital, Brooklyn, New York

C.V. Ramana Reddy

Department of Medicine The Methodist Hospital, Brooklyn, New York

William H. Becker

Department of Medicine The Methodist Hospital, Brooklyn, New York

K.C. Oh

Department of Medicine The Methodist Hospital, Brooklyn, New York

S.G. Kim

Department of Medicine The Methodist Hospital, Brooklyn, New York

His bundle electrograms were recorded in 12 patients before and after the intravenous administration of 5 mEq of potassium. Antegrade and retrograde refractory periods were determined with the extrastimulus technique. The AH interval was 84 ± 7 msec before and 89 ± 7 msec after potassium (P < 0.05). The AH interval at an atrial pacing rate of 140/minute was 129 ± 13 msec be fore and 143 ± 16 msec after potassium (P < 0.02). The effective refractory pe riod of the atrium was 264 ± 9 msec before and 280 ± 9 msec after potassium ( P < 0.001). Thus small amounts of potassium delay conduction at the atrial and AV nodal level.

Angiology, Vol. 31, No. 10, 666-676 (1980)
DOI: 10.1177/000331978003101003


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