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Angiology
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Selective Coronary Angiography with Iodamide

A Comparison of Myocardial Toxicity of Two Contrast Media

Jüri V. Kaude

Department of Diagnostic Radiology, University Hospital, Lund, Sweden, Department of Cardiology. University Hospital, Lund, Sweden

Anders Lunderquist

Department of Diagnostic Radiology, University Hospital, Lund, Sweden, Department of Cardiology. University Hospital, Lund, Sweden

Stig Persson

Department of Diagnostic Radiology, University Hospital, Lund, Sweden, Department of Cardiology. University Hospital, Lund, Sweden

Krister Arnman

Department of Diagnostic Radiology, University Hospital, Lund, Sweden, Department of Cardiology. University Hospital, Lund, Sweden

The myocardial toxicity of iodamide (Jodomiron 380) in selective coronary angiography was compared with that of metrizoate (Isopaque coronar). Electrocardiographic changes, systolic blood pressure and heart rate were registered and compared in a total of 106 injections. Both contrast media produced transient changes in ST-segment and T-wave, reduced the heart rate and systolic blood pressure. Differences noted were: a more marked hypotensive effect after injection of Jodomiron into the left coronary artery, and a higher frequency of moderate electrocardio graphic changes at injection of Isopaque into the right coronary artery. Because of the small number of registrations, however, these differences were not conclusive. The diagnostic quality of examination with both contrast media was excellent.

Angiology, Vol. 25, No. 7, 449-456 (1974)
DOI: 10.1177/000331977402500704
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