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First published on April 2, 2008
Angiology 2008, doi:10.1177/0003319707310275
© 2008 SAGE Publications

Article

Ostial Lesions of Left Main and Right Coronary Arteries: Demographic and Angiographic Features

Sirous Darabian*, Ali Amirzadegan, Hakimeh Sadeghian, Saeed Sadeghian, Ali Abbasi, and Maria Raeesi

* To whom correspondence should be addressed. E-mail: darabian{at}irimc.org.


  Abstract
In 258 patients with left main tract disease, the atherosclerotic risk factors were compared between patients with ostial and nonostial lesions of the left main coronary artery. Also, it was done for patients with ostial right coronary artery. Women were more likely to have ostial left main coronary artery and/or ostial right coronary artery. A multivariate logistic regression analysis revealed that the female sex (odds ratio: 2.336) and hypertriglyceridemia (odds ratio: 1.004) were independent risk factors of ostial left main coronary artery lesion. For ostial right coronary artery lesion, the female sex and family history of coronary artery disease were independent predictors. Ostial left main coronary artery and right coronary artery lesions were strongly correlated. The demographic and clinical profiles of ostial stenosis suggest that this group may represent a distinct entity, different from the more common atherosclerotic left main trunk stenosis (LMTD). The female sex and serum triglyceride level can be considered as independent predictors of ostial left main tract disease.


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